“Endosteal Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis”
Mark Esposito ’11, a graduate student in the Kang lab was awarded the pre-doctoral F31 fellowship for his research proposal entitled Exploration of the dynamics of E-selectin interaction in breast cancer metastasis.
The colonization of distant organs by cancerous cells is a process responsible for the vast majority of deaths in oncology. Mark’s research seeks to identify molecular interactions that impact the dissemination and progression of these etastatic cancers with the goal of providing new therapeutic targets. This project focuses on how golgi-resident enzymes and extracellular membrane proteins interact to control the initial communication between cancer cells and the organs which they invade.
Friday, September 29, 1:45 pm in BiHall 216
Mark is pursuing a Ph.D. in Molecular Biology at Princeton University. He recently opened a new scientific news website that translates breaking research to the public.
Mark was also recently awarded two fellowships, the New Jersey Commission on Cancer Research, and an NIH F31 Award, and received recognition at the Princeton Innovation Forum.