Thanks to Andrew Grant ’17 for sharing this opportunity with us!
The Clinical Genome Resource at the Broad Institute of MIT and Harvard is seeking a motivated individual to work in a cutting-edge environment to serve as a research associate for the Clinical Genome Resource (ClinGen). ClinGen is an NIH-funded program that is building authoritative resources to define the clinical relevance of genes and variants for use in precision medicine and research (www.clinicalgenome.org). This position would begin with training within our variant and gene-curation team which supports variant classification and gene-disease validity assessment followed by supporting an array of ClinGen disease-specific Expert Panel activities and affiliated projects within ClinGen and at the Broad Institute.
PRINCIPAL DUTIES AND RESPONSIBILITIES
Support ClinGen curation activities
Research the significance of variants and genes through literature and data review
Classify variant- and gene-disease associations
Support research projects that require curation of genomic knowledge
Support the ClinGen’s mission to provide better access to genomic data
Support the sharing of curated knowledge with the community
Assist laboratories with data submission to ClinVar (www.ncbi.nlm.nih.gov/clinvar)
Collect data from locus-specific databases to deposit into ClinVar
Assist in the development of software tools for supporting variant and gene curation
Assist in resolving variant interpretation differences between ClinVar submitters
Assist Clinical Domain WGs in supporting gene and variant curation programs
Support the writing of ClinGen research publications
Support other projects related to genetic and genomic testing and research at the Broad
In addition, the Research Associate should possess excellent organizational skills and the ability to interact effectively with a local team at the Broad Institute and an international network of laboratories and data sources and balance and manage multiple tasks and projects independently. We request a minimum of a two-year commitment.
Start date: May or June 2019
Qualifications: BA or BS degree in the sciences
Job location: The Broad Institute of MIT and Harvard, 105 Broadway, Cambridge, MA
Reports to: Heidi Rehm, PhD, Principal Investigator, Clinical Genome Resource
Got a goal? Goaloop it! Like YouTube is for videos and Amazon is for products, Goaloop is for goals.
Goaloop is a tech start-up based in Manhattan and they recently reached beta launch! Join them and become important members of their small, innovative team – which is growing. Goaloop helps you reach your goals and connects the world through goals. Got a goal? Goaloop it! State your goal on Goaloop, and people and resources come to you to help you achieve it. Connecting goals expands social circles and increases commercial opportunities. Connecting goals, we can achieve anything together!
The National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) seeks highly-motivated applicants for scientific administrative openings as a Scientific Program Analyst in Bethesda, MD.
This is an exciting opportunity for recent graduates in the biological sciences to gain first-hand experience in and broad exposure to how cutting-edge medical research is supported. It is an ideal position for applicants seeking a two-year appointment prior to enrolling in graduate or professional school. The position supports the genomics research programs and consortia funded by NHGRI. The Scientific Program Analyst will carry out administrative duties and scientific analyses in support of Program Directors in the NHGRI Extramural Research Program, which awards grants to the academic and biotechnology communities to carry out basic and applied genomics research. Please see https://www.genome.gov/researchfunding/ for more information about NHGRI.
There are two RA positions open in Pediatric Oncology at Dana Farber. Dr. Birgit Knoechel writes, “The overarching goal of my lab and the Lohr lab is to study the biology of therapeutic resistance in cancer with a particular focus on genomic and epigenetic aberrations. We use single cell/low input genomics, epigenomics and other single cell technology to define dynamic changes in tumor model systems and primary patient samples with a disease focus on hematologic malignancies and sarcoma. We also use a wide variety of tools to study underlying mechanisms, which span the entire spectrum from biochemistry, functional perturbation to in vivo mouse models.”
Click on the titles to learn how to apply.
RA Epigenetics – The Dana-Farber Cancer Institute is looking for an exceptional candidate for a unique Research Associate position. This position affords the exciting opportunity to be part of a research effort at Dana-Farber Cancer Institute aiming to delineate epigenomic aberrations in cancer and discover novel therapeutic targets. The candidate will assist in the development of cancer models from primary human tumors and human cell lines that represent different cellular lineages and drug-resistant states. He/she will use modern next generation sequencing techniques to characterize the chromatin state of these tumors and modern functional perturbation techniques including lentiviral knockdown and CRISPR/Cas9 genome editing tools. He/she will test the model systems in immuno-compromised mice for their ability to form tumors and to test for drug responses. He/she will be part of a multi-disciplinary team that evaluates new technologies and approaches to discover and validate novel systemic cancer biology.
RA Genomics – Dana-Farber Cancer Institute is looking for an exceptional candidate for a unique Research Associate position. This position affords the exciting opportunity to be part of a research effort at Dana-Farber Cancer Institute aiming to delineate genomic aberrations in cancer biology and discover novel therapeutic targets. He/she will use modern next generation sequencing techniques to characterize genomic aberrations and modern functional perturbation techniques including CRISPR/Cas9 and other genome editing tools. He/she will use various model systems to test for drug responses and determine mechanisms of resistance to drugs, including novel immunotherapies. He/she will be part of a multi-disciplinary team that evaluates new technologies and approaches to discover and validate novel systemic cancer biology.
This position is brought to you by Annie Cowan ’18 – application deadline February 3rd:
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, they provide compassionate and comprehensive care to patients of all ages; they conduct research that advances treatment; they educate tomorrow’s physician/researchers; they reach out to underserved members of their community; and they work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The Clinical Research Coordinator works within the clinical research program and supports the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator(s) and the DFCI Clinical Trials Office. The CRC will be responsible for the primary data collection and management of patient clinical information as it pertains to participation in clinical trials. Ensures timely collection of protocol related samples including shipment to outside entities as required. Maintains regulatory binders and ensures study compliance with all state, federal, and IRB requirements. May be responsible for IRB protocol submissions (amendments, continuing reviews, and minimal risk protocols). This individual may also screen patients for protocol eligibility, obtain informed consent, and register study participants to clinical trials. Some travel may be required
Gartner, Inc. (NYSE: IT) is the world’s leading research and advisory company and a member of the S&P 500. They equip business leaders with indispensable insights, advice and tools to achieve their mission-critical priorities today and build the successful organizations of tomorrow.
The IT Rotational Program is a two-year development opportunity for high-potential individuals who are completing a Computer Science or Data Science Bachelor’s degree. This is a unique opportunity to spend 24 months rotating through diverse aspects of Gartner’s IT organization. Associates will rotate through a variety of projects based upon interests and business needs, gaining exposure to varied technologies.
What you’ll do:
Rotate through a full-time, two year rotational program to gain exposure to various business functions prior to being integrated into one of the IT business units.
Design, implement, and test various applications and/or services using a range of technologies
Contribute to the review and analysis of business requirements
Collaborate on architecture and technical design discussions
Perform and participate in code reviews, peer inspections and technical design/specifications
Document and review detailed design
Focus on mid-size to large projects for the development of NLP and Machine learning solutions employing a working knowledge of SDLC, SCRUM, and Agile methodologies.
What you’ll need:
Graduating college senior earning a Bachelor’s degree in Computer Science, Data Science, or related engineering field
Formal training/class work in software development Java/.NET/C++/etc.)
Motivated, high-potential performers with demonstrated ability to influence and lead
Web based application development experience is a plus (Java/J2EE preferred)
Java and SQL Experience with a relational database.
JQuery, Twitter Bootstrap experience is a plus
Demonstrable knowledge in natural language processing or text mining
Knowledge with NLP tools such as NLTK
Hands on knowledge implementing data mining and machine learning models
Hands on knowledge with Big Data tools such as Hadoop, Spark is a plus